The Foundation recently funded The Laney Jaymes Foundation Research Project in Pediatric Vasculopathy for the Department of Neurology at the Johns Hopkins University.
Moyamoya disease specifically and vasculopathy in general are extremely variable in presentation and outcome. Laney had a progressive, devastating form of moyamoya. The medical community does not have a good sense of what factors determine the course of the disease and the proper treatment for children with different severity of the disease. What makes one child’s disease progressive and severe when another child might have a mild course?
The study will commence a retrospective review of all cases of pediatric vasculopathy treated at the Johns Hopkins Hospital. The study will collect information about a number of variables (age at onset of symptoms, demographic information, vessels affected, laboratory studies, time to surgical revascularization, time to diagnosis, etc.) to determine which factors are correlated with outcome. John Hopkins intends to use this data to plan future studies of pediatric vasculopathy in coordination with other medical centers, and to glean information about this rare but potentially devastating disorder.